Clayton Lane is located just southeast of central downtown Denver in the Cherry Creek district.

Parking structures are located off of 2nd Ave. in the Whole Foods Market parking lot and off of 2nd Avenue at Columbine Street. Metered street parking is also available.

From central downtown Denver: Take Speer Blvd. south to 1st Ave. Turn left on 1st Ave. and follow to Josephine St.

From I-70 to the north: Exit on to Colorado Blvd. south. Follow Colorado Blvd. south to 1st Ave., turn right on 1st Ave. and continue to Detroit St.

From I-25 to the south: Exit on to Colorado Blvd. north. Follow Colorado Blvd. north to 1st Ave., turn left on 1st Ave. and continue to Detroit St.

From I-225 to the east: Travel north on I-225 to I-70 west. Follow I-70 west and exit on to Colorado Blvd. south. Follow Colorado Blvd. south to 1st Ave., turn right on 1st Ave. and continue to Detroit St.

Clayton Lane can be accessed by city bus lines 6 and 24 on Josephine Street and 1st Avenue.